Idiopathic Adrenal Insufficiency Isolated Addison's Disease or Autoimmune Polyglandular Syndrome Typ I and II
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Erythema annulare centrifugum: association with autoimmune polyglandular syndrome type 1
Autoimmune polyendocrine syndromes are a heterogeneousgroup of rare diseases characterized by autoimmune activityagainst more than one endocrine organ, although non-endocrineorgans can also be affected. We report the association of APS Iwith erythema annulare centrifugum in an 18-years-old male whopresented with multiple figurate erythema spreading on his trunkand extremities along with a histo...
متن کاملAutoantibodies to human tryptophan hydroxylase and aromatic L-amino acid decarboxylase.
OBJECTIVE To assess the prevalence of autoantibodies (Abs) to tryptophan hydroxylase (TPH) and aromatic l-amino acid decarboxylase (AADC) in patients with different autoimmune diseases and to analyse their respective epitopes. DESIGN TPH and AADC Abs were measured in an immunoprecipitation assay using (35)S-labelled full-length and fragments of TPH and AADC. METHODS Patients with different ...
متن کاملAutoimmune Polyglandular Syndrome Type 2 (APS-2) in a 70-Year-Old Woman: A Case Report
Type2 autoimmune polyglandular (Schmidt) syndrome is defined by the occurrence of at least 2 out of 3 of the following manifestations, Addison's disease, Hypothyroidism and Type 1 diabetes mellitus. APS2 is a rare condition with an incidence of 1–2/100 000 per year. Prevalence of APS-2 is most happening in the range of 20-40 years of age. Here we present a patient who complained about loss of ...
متن کاملAutoimmunity as the most frequent cause of idiopathic secondary adrenal insufficiency: report of 111 cases.
The origin of the isolated secondary adrenal insufficiency is unknown in most cases. An observation of a group of over 100 patients with secondary adrenal insufficiency and coexisting autoimmune abnormalities suggests that autoimmunity could be a frequent cause of idiopathic secondary failure, similarly as in Addison's disease. We studied 176 patients with idiopathic isolated secondary adrenal ...
متن کاملSteroid Therapy in Adrenal Insufficiency
Addison’s disease or autoimmune adrenalitis: These are autoimmune conditions, constituting 80% of all cases. Autoimmune adrenalitis may be part of Type 2 autoimmune polyglandular syndrome, which can include type 1 diabetes, hyperthyroidism, and autoimmune thyroid disease (also known as Hashimoto’s thyroiditis), and Hashimoto’s disease. Hypogonadism may also present with this syndrome. Other dis...
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تاریخ انتشار 2008